US Medical Franchise Head, Hematology

Introduction to Role At AstraZeneca, we turn ideas into life-changing medicines. Working here means being entrepreneurial, thinking big, and collaborating to make the impossible a reality. We are passionate about the potential of science to address the unmet needs of patients around the world and focus on areas where we believe we can meaningfully change the course of disease. As the US Medical Franchise Head, Hematology , you will provide strategic and scientific leadership for the US Hematology Medical Affairs organization. You will be accountable for defining and delivering the US Medical strategy across the hematology franchise, translating emerging science and insights from the healthcare ecosystem into strategies that advance patient care and enhance the impact of our portfolio. You will lead a high-performing organization spanning headquarters and field medical teams, partner closely with Global Medical, R&D, Commercial, Market Access, Real-World Evidence, Government Affairs, and Patient Advocacy, and serve as a senior medical voice for the hematology franchise in the US. Accountabilities • Set and lead the US Medical strategy for the Hematology franchise , ensuring alignment with US business priorities, Global Medical strategy, lifecycle plans, and evolving patient, provider, payer, and healthcare system needs. • Deliver a coordinated US medical evidence generation strategy across the hematology portfolio, including late-phase and post-approval studies, real-world evidence, health outcomes research, externally sponsored research, and other evidence-generation activities developed to address clinically relevant evidence gaps. • Lead the US Hematology Medical Affairs organization , including headquarters and field medical teams, crafting an environment characterized by scientific excellence, innovation, accountability, inclusion, collaboration, and high performance. • Provide strategic oversight and leadership across the hematology portfolio , ensuring Medical strategies and plans support assets across different stages of the product lifecycle, from launch readiness and indications under development through lifecycle management and mature brands. • Build organizational capability and a strong talent pipeline by establishing clear accountabilities, developing and retaining outstanding talent, strengthening succession plans, and encouraging continuous learning and improvement. • Generate and translate actionable medical insights from healthcare professionals, scientific leaders, patients, payers, treatment centers, and other partners to advise US and Global Medical strategy, evidence-generation priorities, clinical development, and portfolio decisions. • Lead strategic engagement with external scientific and medical leaders , including hematologists, oncologists, investigators, academic institutions, collaborative groups, medical societies, and other organizations crafting the future of hematology care. • Advance the scientific exchange strategy for the franchise , ensuring field medical teams are equipped to engage credibly and stays in sync with external partners regarding evolving science, treatment paradigms, unmet needs, and the AstraZeneca hematology portfolio. • Partner across functions and geographies , including R&D, Global Medical Affairs, Commercial, Market Access, Real-World Evidence, HEOR, Regulatory, Government Affairs, Corporate Affairs, and Patient Advocacy, to ensure a coordinated approach to advancing patient outcomes. • Serve as a senior US Medical representative for Hematology in key governance forums, providing scientific and medical leadership to portfolio, investment, lifecycle, launch, and business development decisions. • Identify emerging trends and innovations in hematology , including new therapeutic modalities, diagnostics, biomarkers, treatment pathways, and models of care, and translate these developments into implications for AstraZeneca's portfolio and Medical strategy. • Champion compliant, ethical, and patient-centered Medical Affairs practices , ensuring activities meet applicable regulatory requirements, company policies, scientific standards, and expectations for medical governance. Essential Skills/Experience • Sophisticated scientific or clinical degree such as MBBS, MD, DO, PharmD, PhD, or equivalent medical education. Medical specialty training is strongly preferred. • Significant experience in the pharmaceutical/biotechnology industry, including senior leadership experience within Medical Affairs and/or clinical development . • Demonstrated expertise in hematology and/or hematologic oncology , with solid understanding of the US treatment landscape, evolving standards of care, clinical development, and healthcare environment. • Validated experience developing and accomplishing portfolio- or franchise-level Medical strategies , ideally across multiple assets, indications, and stages of the product lifecycle. • Demonstrated success leading leaders and multidisciplinary Medical Affairs organizations , including headquarters and field medical teams. • Consistent track record in evidence generation , including the ability to translate scientific and clinical evidence gaps into coordinated evidence plans. • Significant experience engaging external scientific authorities, investigators, academic institutions, medical societies, and other healthcare partners . • Proven track record to influence and lead across sophisticated, highly matrixed organizations and to build positive relationships across Medical, R&D, Commercial, Market Access, and other functions. • Outstanding scientific judgment, executive communication, critical thinking, and ability to make decisions in a rapidly evolving therapeutic environment. Desirable Skills/Experience • Deep expertise in one or more areas of hematology, including hematologic malignancies, rare blood disorders, or other relevant hematology disease areas . • Experience supporting major U